The 2nd International Conference on Informatics and Computational Sciences (ICICoS 2018) aims to provide a platform for Researchers, Academicians, Professionals, Engineers, and also students to share their research ideas and results of research especially in the field of informatics, computational science and related field. The highlight of ICICoS 2018 is “The Challenge of Industry 4.0 and Its Impact on Society”. This highlight is selected inline with Indonesian Goverment Policy in Industry Sector. In addition, this highlight is chosen so that researchers, Academicians, Professionals, Engineers, and also students are encouraged to perform research on this field.